DR. CLAIMS THAT PRECISION ONCOLOGY MAY BE USED TO DECODE CANCER.

With the use of cutting-edge technology known as precision oncology, this is not a scene from a science fiction movie but rather the reality of cancer therapy today.

Imagine having a cancer treatment plan that is as individualized as a patient's fingerprints, one that is tailored to the precise features of each patient's tumour. This isn't a scene from a science fiction movie; it's the reality of cancer therapy in the present day, thanks to cutting-edge technology known as precision oncology. The medical oncology consultant at Kokilaben Dhirubhai Ambani Hospital in Mumbai, Dr Vaibhav Choudhary, spoke with Swapnil Mishra.

By adapting the treatment to each patient's specific genetic profile and assisting in the selection of the most successful treatments from chemotherapy, targeted therapy, or immunotherapy, the integration of genomics has enhanced precision oncology.

 

JUST WHAT DOES GENETIC TESTING ENTAIL?

About 10% of all cancers are hereditary, and they are brought on by genetic changes that are passed down from one's parents. People who possess specific gene variations are more likely to acquire various malignancies, including but not limited to breast, ovarian, colon, and pancreatic cancer. These diseases can occur in these people. Hereditary cancer clinics with specialised teams provide genetic counselling, testing, and individualised risk assessments for those with a family history of cancer under certain circumstances. By detecting certain genetic abnormalities, genetic testing is a potent tool that may be used to assess a person's lifetime risk of acquiring cancer.

The existence of numerous cancer-related genes, including BRCA1, BRCA2, TP53, and PTEN, which are linked to an increased risk of acquiring particular malignancies, can be identified with the use of germline cancer panel testing. The treatment of patients can be greatly enhanced by discovering these genetic variants and using that information to make decisions about preventative actions like expanded screening or risk-reducing operations. The results can also direct how targeted medicines are used.

A remarkable turnaround time of just five days is provided by the PanPredict lung cancer panel, which examines 11 predictive genes for mutations and fusions in advanced lung tumours. With the help of this quick, accurate, and focused testing, doctors can make treatment decisions much more quickly, offering cancer patients a vital advantage in their battle.

 

AND WHAT BENEFIT DOES THE MOLECULAR TUMOUR BOARD OFFER?

 Based on the genetic abnormalities in a patient's cancer, a molecular tumour board brings specialists from different specialities to evaluate the best therapy choices for specific individuals. By addressing diagnostic, prognostic, and therapeutic issues and helping to make the best clinical care decisions possible, these sessions provide a comprehensive and precise approach to patient care. Every aspect of the fight against cancer must be

  

WHAT IS PRECISION ONCOLOGY EXACTLY?

 Modern methods like precision oncology are changing how we think about and treat cancer. Precision oncology, sometimes referred to as personalized cancer therapy, is a cutting-edge cancer treatment method that considers the distinct genetics of the patient and the illness.

Precision oncology develops therapies that are customized to the distinct genetic abnormalities identified in each person's cancer cells as opposed to employing a one-size-fits-all approach. Upon receiving a cancer diagnosis, a patient's tumour can be sequenced to determine the genetic abnormalities fueling the disease's progression. If we can target these mutations, which are comparable to cancer's Achilles' heel, we may be able to halt the disease in its tracks. Modern cancer treatment has revolutionized the fight against this devastating disease. With advancements in precision medicine, targeted therapies, immunotherapy, and breakthroughs in genetic research, patients now have better chances of successful outcomes. Improved screening methods and early detection techniques enable timely intervention. Additionally, supportive care measures enhance patients' quality of life during treatment. These remarkable developments instil hope, empower individuals, and contribute to a brighter future in the battle against cancer.